Attackers have found a way to exploit a number of bugs in peer-to-peer servers to initiate DDoS attacks. The most aggressive of these peer-to-peer-DDoS attacks exploits DC++. Peer-to-peer attacks are different from regular botnet-based attacks. With peer-to-peer there is no botnet and the attacker does not have to communicate with the clients it subverts. Instead, the attacker acts as a 'puppet master,' instructing clients of large peer-to-peer file sharing hubs to disconnect from their peer-to-peer network and to connect to the victim’s website instead. As a result, several thousand computers may aggressively try to connect to a target website. While a typical web server can handle a few hundred connections/sec before performance begins to degrade, most web servers fail almost instantly under five or six thousand connections/sec. With a moderately big peer-to-peer attack a site could potentially be hit with up to 750,000 connections in a short order. The targeted web server will be plugged up by the incoming connections. While peer-to-peer attacks are easy to identify with signatures, the large number of IP addresses that need to be blocked (often over 250,000 during the course of a big attack) means that this type of attack can overwhelm mitigation defenses. Even if a mitigation device can keep blocking IP addresses, there are other problems to consider. For instance, there is a brief moment where the connection is opened on the server side before the signature itself comes through. Only once the connection is opened to the server can the identifying signature be sent and detected, and the connection torn down. Even tearing down connections takes server resources and can harm the server.

This method of attack can be prevented by specifying in the p2p protocol which ports are allowed or not. If port 80 is not allowed, the possibilities for attack on websites can be very limited.